Bhutani Lab  

Publications

  1. Taylor S.B., Smeriglio P., Dhulipala S., Rath M. and Bhutani N. (2013) An increase in global 5hmC levels marks Osteoarthritic chondrocytes. Arthritis & Rheum (in press).
  2. Bhutani N., Decker M.N., Brady J.J., Bussat R.T., Burns D.M., Corbel S.Y. & Blau H.M. (2013) A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells. FASEB J. 2013 Mar;27(3):1107-13.
  3. Bhutani N., Piccirillo R., Hourez R., Venkatraman P. & Goldberg A.L. (2012) Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes. J Biol. Chem., 287(21), 17471-82
  4. Bhutani N., Burns D.M. & Blau H.M. (2011) DNA demethylation dynamics. Cell, 146(6), 866-72
  5. Bhutani N., Brady J., Damian M.R., Sacco A., Corbel, S.Y. & Blau H.M. (2010) Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature, 463(7284), 1042-7
  6. Palermo A., Doyonnas R., Bhutani N., Alkan O., Pomerantz J., Blau H.M. (2009) Nuclear reprogramming in heterokaryons is rapid, extensive and bidirectional. FASEB J 23(5), 1431-40
  7. Bhutani N., Venkatraman P., Goldberg A.L. (2007) Puromycin-sensitive aminopeptidase is the major cytosolic protease responsible for degrading poly-glutamine peptides released by the proteasome. EMBO J  26(5), 1385-96
  8. York I.A., Bhutani N., Zendcien S., Goldberg A.L., Rock K.L. (2006) Tripeptidyl peptidase II (TPPII) trims long antigenic precursors, but is not required for most MHC Class I antigen presentation. J.Immunology 177(3), 1434-43
  9. Chang S.C, Momberg F., Bhutani N., Goldberg A.L. (2005) A molecular ruler mechanism for the length preference of ERAP1, a key enzyme in antigen presentation. Proc. Natl. Acad. Sci. 102(47), 17107-12.
  10. Bhutani N., Udgaonkar J.B. (2003) Folding sub-domains of thioredoxin characterized by Native state hydrogen-exchange. Protein Sci. 12 (8), 1719-31.
  11. Bhutani N., Udgaonkar J.B. (2002) Chaperonins as protein folding machines. Curr. Sci. 83 (11), 1337-1351.
  12. Bhutani N., Udgaonkar J.B. (2001) GroEL channels the folding of thioredoxin along one kinetic route. J. Mol. Biol. 314 (5), 1167-1179.
  13. Bhutani N., Udgaonkar J.B. (2000) A thermodynamic coupling mechanism can explain the GroEL-mediated acceleration of the folding of barstar. J. Mol. Biol. 297(5), 1037-1044.
  14. Bhutani N., Ranjith M.R., Yameen M., Singh N., Dev V., Pillai C.R., Ansari M.A., Sharma Y.D., (1998) Genetic diversity among fields isolates of P. falciparum in India. Curr. Sci. 75, 160-163.
  15. Sharma YD, Fakruddin JM, Bhutani N, Kaushik R, Raina OK & Sharma I. (1997) Strain variation and gene hunting in Malaria. Indian J Clin. Biochem. 12(Suppl 1): 49-51.

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